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Editorial Comment
'Where there's smoke': longitudinal cognitive disintegration after postoperative delirium?
- Elie Matar and Robert D Sanders.
- Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia; Forefront Research Team, Brain and Mind Centre, University of Sydney, Sydney, Australia. Electronic address: elie.matar@sydney.edu.au.
- Br J Anaesth. 2023 Jul 1; 131 (1): 151-5.
AbstractPostoperative delirium is an important complication of surgery and is associated with poor long-term cognitive outcomes, although the neural basis underlying this relationship is poorly understood. Neuroimaging studies and network-based approaches play an important role in our understanding of the mechanism by which delirium relates to longitudinal cognitive decline. A recent resting state functional MRI study is reviewed, which shows reduced global connectivity up to 3 months after delirium, supporting recent models of delirium and opening the door for applying this approach to understanding the complex inter-relationship between delirium and dementia.Copyright © 2023 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.
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