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Internal medicine journal · Mar 2023
Putting the best foot forward when treating newly diagnosed multiple myeloma.
- Sueh-Li Lim and Andrew Spencer.
- Alfred Health, Melbourne, Victoria, Australia.
- Intern Med J. 2023 Mar 1; 53 (3): 318322318-322.
AbstractMultiple myeloma (MM) remains an incurable disease. In Australia, patients receive sequential lines of novel agent (NA)-based lines of therapy (LOTs), including proteasome inhibitors, immunomodulatory drugs and CD38-targeting monoclonal antibodies within the constraints of the pharmaceutical benefits scheme. We propose that induction with a quadruplet incorporating all three drug classes and dexamethasone at diagnosis is the best approach to gain disease control.© 2023 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.
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