• Latefa Hamad Al Fryan, Mahasin Ibrahim Shomo, and Malik Bader Alazzam.
• Department of Educational Technology, College of Education, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
• Medicina (Kaunas). 2023 Mar 1; 59 (3).

AbstractBackground and Objectives: The classification of breast cancer is performed based on its histological subtypes using the degree of differentiation. However, there have been low levels of intra- and inter-observer agreement in the process. The use of convolutional neural networks (CNNs) in the field of radiology has shown potential in categorizing medical images, including the histological classification of malignant neoplasms. Materials and Methods: This study aimed to use CNNs to develop an automated approach to aid in the histological classification of breast cancer, with a focus on improving accuracy, reproducibility, and reducing subjectivity and bias. The study identified regions of interest (ROIs), filtered images with low representation of tumor cells, and trained the CNN to classify the images. Results: The major contribution of this research was the application of CNNs as a machine learning technique for histologically classifying breast cancer using medical images. The study resulted in the development of a low-cost, portable, and easy-to-use AI model that can be used by healthcare professionals in remote areas. Conclusions: This study aimed to use artificial neural networks to improve the accuracy and reproducibility of the process of histologically classifying breast cancer and reduce the subjectivity and bias that can be introduced by human observers. The results showed the potential for using CNNs in the development of an automated approach for the histological classification of breast cancer.

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