• Medicine · Mar 2023

    Case Reports

    A case report of T cell/histiocyte-rich large B cell lymphoma misdiagnosed as lymphomatoid papulosis.

    • Taekwoon Kim, Jisung Kim, and Joonsoo Park.
    • Department of Dermatology, School of Medicine, Daegu Catholic University, Daegu, Korea.
    • Medicine (Baltimore). 2023 Mar 31; 102 (13): e33407e33407.

    RationaleT cell/histiocyte-rich large B cell lymphoma (THRLBCL) is an uncommon B cell lymphoma characterized by < 10% large neoplastic B cells in a background of abundant T cells and frequent histiocytes. If a skin lesion is the first clinical sign of lymphoma, the diagnosis might be difficult and misdiagnosed.Patient ConcernsA 60-year-old woman presented with multiple erythematous umbilicated nodules on her left upper back for 3 months.DiagnosesThrough punch biopsy of the back lesion and additional excisional right inguinal lymph node biopsy, the patient was diagnosed with cutaneous metastasis of THRLBCL.InterventionsThe patient was referred to the Hemato-oncology Department for chemotherapy.OutcomesR-CHOP chemotherapy is currently in progress, and some skin lesions show improvement.LessonsSkin lesions might be the first clinical sign of THRLBCL and when THRLBCL is suspected, careful further evaluation is essential for accurate diagnosis and treatment.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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