• Mingyue Fan, Junshu Gao, Na Li, Wei Jin, Yang Liu, Xueqian Zhang, and Peiyuan Lv.
• Department of Neurology, Hebei General Hospital, Shijiazhuang, Hebei, China.
• Medicine (Baltimore). 2023 Mar 31; 102 (13): e33375e33375.

RationaleBilateral medial medullary infarction is a rare stroke subtype. To investigate its clinical manifestations, etiology, imaging features and thrombolytic effect, We here in reported a patient with acute ischemic stroke in the bilateral medial medullary and reviewed the related literatures.Patients ConcernA 64-year-old female was taken to our hospital after 4.5 hours of dizziness in the morning, followed by somnolence and limb weakness. She gradually worsened into a rapidly progressive tetraparesis and slurred speech.DiagnosesDiffusion weighted imaging exhibited a "heart appearance" sign in bilateral medial medulla oblongata, and high-resolution magnetic resonance imaging suggested the left vertebral artery-4 thromboembolism.InterventionsTimely intravenous thrombolysis was performed.OutcomeAfter intravenous thrombolysis, the patient's symptoms did not worsen in a short time. Although the symptoms were aggravated in the later stage, they were alleviated after active treatment.LessonsDiffusion weighted imaging can assist in the early diagnosis of bilateral medial medullary infarction, which will help in the decision to proceed with intravenous thrombolysis therapy. High-resolution magnetic resonance imaging should be improved as soon as possible, which can provide basis for the next intravascular interventional therapy.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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