• Ogechukwu N Iloanusi, Nneka I Iloanusi, and Arun A Ross.
• Department of Electronic and Computer Engineering, University of Nigeria, Enugu, Nigeria.
• Curr Med Res Opin. 2023 May 1; 39 (5): 719729719-729.

ObjectivesA world-wide immunization project was launched at the peak of COVID-19 pandemic to contain and minimize the adverse effects of SARS-CoV-2 virus. We carried out a series of statistical analyses in this paper to determine, confirm and quantify the impact of the vaccinations on COVID-19 cases and mortalities, amidst critical confounding factors-temperature and solar irradiance.MethodsThe experiments in this paper were carried out on the world data, data from 21 countries, and the five major continents. The significance of the 2020-2022 vaccinations on the COVID-19 cases and mortalities response data were evaluated via Hypotheses' tests. Correlation coefficient analyses were carried out to determine the extent of the relationship between vaccination coverage and corresponding COVID-19 mortalities data. The impact of vaccination was quantified. The effects of the weather factors-temperature and solar irradiance, on COVID-19 cases and mortalities data were analyzed.ResultsThe series of hypotheses tests carried out reveal that vaccinations did not affect cases; however, vaccinations significantly impacted the mean daily mortalities in all five major continents and globally. The correlation coefficient analysis results show vaccination coverage to be highly and negatively correlated with daily mortalities in the world-the five major continents and most of the countries studied in this work. The percentage reduction in mortalities as a result of wider vaccination coverage was indeed significant. Temperature and solar irradiance impacted daily COVID-19 cases and mortalities data during the vaccination and post-vaccination periods.ConclusionResults show that the world-wide vaccination against COVID-19 project had a significant impact in reducing mortalities and minimizing the adverse effects due to COVID-19 globally, in all five (5) major continents of the world and the countries studied in this work, however, temperature and solar irradiance still had effects on COVID-19 response in the vaccination eras.

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