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Med. Clin. North Am. · May 2023
ReviewDrug-Induced Liver Injury due to Biologics and Immune Check Point Inhibitors.
- Fernando Bessone and Einar S Björnsson.
- Facultad de Ciencias Médicas, Hospital Provincial del Centenario, University of Rosario, School of Medicine, Urquiza 3101, Rosario 2000, Argentina. Electronic address: bessonefernando@gmail.com.
- Med. Clin. North Am. 2023 May 1; 107 (3): 623640623-640.
AbstractBiological agents have in the last two decades become very important therapeutic agents, particularly for the treatment of various autoimmune disorders. The most widely used biologics are the tumor necrosis factor-α (TNF-α) receptor antagonists: infliximab, adalimumab, and etanercept. Other commonly used biological agents are interleukin (IL)-1 receptor antagonist (Anakinra), interleukin (IL)-6 receptor antagonist (tocilizumab), and CD20 surface antigen antagonist (rituximab). The current review will however focus on TNF-α receptor antagonists.Copyright © 2022 Elsevier Inc. All rights reserved.
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