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Review Case Reports
[Rare manifestations of monoclonal gammopathies: About two clinical cases and literature review].
- Q Perlot, C Hermans, and M-C Vekemans.
- Service d'hématologie, cliniques universitaires Saint-Luc, avenue Hippocrate, 10, 1200 Bruxelles, Belgique. Electronic address: quentinperlot@hotmail.com.
- Rev Med Interne. 2023 Jun 1; 44 (6): 307310307-310.
IntroductionMonoclonal gammopathies are common over the age of 50. Patients are usually asymptomatic. However, some patients present with secondary clinical manifestations, which are now grouped under the entity « Monoclonal Gammopathy of Clinical Significance » (MGCS).Case ReportHere, we report two rare cases of MGCS: an acquired von Willebrand syndrome (AvWS) and an acquired angioedema (AAE).ConclusionThe discovery of a decrease in von Willebrand activity (vWF:RCo) or angioedema in a patient over 50 years of age, in the absence of a family history, should prompt a search for a hemopathy and in particular, a monoclonal gammopathy.Copyright © 2023 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.
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