• Natalia Jaworska, Karla D Krewulak, Emma Schalm, Daniel J Niven, Zahinoor Ismail, Lisa D Burry, LeighJeanna ParsonsJPSchool of Health Administration, Faculty of Health, Dalhousie University, Halifax, NS, Canada., and Kirsten M Fiest.
• Department of Critical Care Medicine, University of Calgary, Calgary, AB, Canada. njaworsk@ucalgary.ca.
• J Gen Intern Med. 2023 Aug 1; 38 (10): 226222712262-2271.

BackgroundAntipsychotic medications do not alter the incidence or duration of delirium, but these medications are frequently prescribed and continued at transitions of care in critically ill patients when they may no longer be necessary or appropriate.ObjectiveThe purpose of this study was to identify and describe relevant domains and constructs that influence antipsychotic medication prescribing and deprescribing practices among physicians, nurses, and pharmacists that care for critically ill adult patients during and following critical illness.DesignWe conducted qualitative semi-structured interviews with critical care and ward healthcare professionals including physicians, nurses, and pharmacists to understand antipsychotic prescribing and deprescribing practices for critically ill adult patients during and following critical illness.ParticipantsTwenty-one interviews were conducted with 11 physicians, five nurses, and five pharmacists from predominantly academic centres in Alberta, Canada, between July 6 and October 29, 2021.Main MeasuresWe used deductive thematic analysis using the Theoretical Domains Framework (TDF) to identify and describe constructs within relevant domains.Key ResultsSeven TDF domains were identified as relevant from the analysis: Social/Professional role and identity; Beliefs about capabilities; Reinforcement; Motivations and goals; Memory, attention, and decision processes; Environmental context and resources; and Beliefs about consequences. Participants reported antipsychotic prescribing for multiple indications beyond delirium and agitation including patient and staff safety, sleep management, and environmental factors such as staff availability and workload. Participants identified potential antipsychotic deprescribing strategies to reduce ongoing antipsychotic medication prescriptions for critically ill patients including direct communication tools between prescribers at transitions of care.ConclusionsCritical care and ward healthcare professionals report several factors influencing established antipsychotic medication prescribing practices. These factors aim to maintain patient and staff safety to facilitate the provision of care to patients with delirium and agitation limiting adherence to current guideline recommendations.© 2023. The Author(s).

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