• Rev Assoc Med Bras (1992) · Jan 2023

    Observational Study

    Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil.

    • Carolina Moro Titton, Marcio Torikachvili, Heloísa M C Rêgo, Eduardo F Medronha, Enio Ziemiecki Junior, Carolina Ribas, Carlos Germano Ceratti, Angelo Alves de Mattos, and Cristiane Valle Tovo.
    • Hospital Nossa Senhora da Conceição - Porto Alegre (RS), Brazil.
    • Rev Assoc Med Bras (1992). 2023 Jan 1; 69 (4): e20220944e20220944.

    ObjectiveThe aim of the present study was to evaluate the outcomes of cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt.MethodsA retrospective longitudinal observational study was carried out evaluating 38 cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt. The outcomes were evaluated in an outpatient follow-up period of 3 months. The assumed significance level was 5%.ResultsThe indications for transjugular intrahepatic portosystemic shunt were refractory ascites in 21 (55.3%), variceal hemorrhage in 13 (34.2%), and hydrothorax in 4 (10.5%) patients. There was development of hepatic encephalopathy in 10 (35.7%) patients after transjugular intrahepatic portosystemic shunt. From the 21 patients with refractory ascites, resolution was observed in 1 (3.1%) patient, and in 16 (50.0%) patients, there was ascites control. Regarding transjugular intrahepatic portosystemic shunt after variceal bleeding, 10 (76.9%) patients remained without new bleeding or hospitalizations in the follow-up period. The global survival in the follow-up period in patients with and without hepatic encephalopathy was 60 vs. 82%, respectively (p=0.032).ConclusionTransjugular intrahepatic portosystemic shunt can be considered in decompensated cirrhotic patients; however, the development of hepatic encephalopathy which can shorten survival should be focused.

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