• Gac Med Mex · Jan 2023

    A novel diagnostic scoring system for pediatric appendicitis based on age and sex-adjusted hematological parameters.

    • Bahattin Aydoğdu, Mustafa Azizoğlu, Serkan Arslan, Gülay Aydoğdu, Erol Basuguy, Fikret Salık, Mustafa Ökten, and Mehmet Hanifi-Okur.
    • Department of Pediatric Surgery.
    • Gac Med Mex. 2023 Jan 1; 159 (2): 103109103-109.

    BackgroundAcute appendicitis diagnosis can sometimes be a real challenge in pediatric patients.ObjectiveTo establish the importance of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and other hematological parameters adjusted for age and sex in the prediction of acute appendicitis, as well as to describe a new scoring system.Material And MethodsMedical records of 946 children hospitalized for acute appendicitis were retrospectively analyzed. A scoring system based on NLR, PLR, lymphocyte/monocyte ratio (LMR), and C-reactive protein (CRP) adjusted for age and sex was developed.ResultsPatients were divided into group I, with negative examination, and group II, with acute appendicitis; mean ages were 12.20 ± 2.31 and 11.56 ± 3.11, respectively. Leukocyte count, neutrophil percentage, NLR, PLR, LMR and PCR were higher in group II. The scores ranged from 0 to 8 points; 4.5 was determined to be the best cut-off point for acute appendicitis with the highest area under the curve (0.96), sensitivity (94%), specificity (86%), positive predictive value (97.5%), negative predictive value (65%), accuracy (92.6%) and misclassification rate (7.4%).ConclusionThe proposed scoring system, calculated based on patient age and gender, can be used for unnecessary surgeries to be avoided.Copyright: © 2023 Permanyer.

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