• Preeyaporn Sarangarm, David E Zimmerman, Brett Faine, Megan A Rech, Tara Flack, Brian W Gilbert, Gavin T Howington, Jessica Laub, Blake Porter, Giles W Slocum, Anne Zepeski, and Caitlin S Brown.
• Department of Pharmacy, University of New Mexico Hospital, Albuquerque, NM 87106, USA. Electronic address: psarangarm@salud.unm.edu.
• Am J Emerg Med. 2023 Jul 1; 69: 136142136-142.

AbstractThe purpose of this article is to summarize pharmacotherapy related emergency medicine (EM) literature indexed in 2022. Articles were selected utilizing a modified Delphi approach. The table of contents from pre-determined journals were reviewed and independently evaluated via the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system by paired authors, with disagreements adjudicated by a third author. Pharmacotherapy-related publications deemed to be GRADE 1A and 1B were reviewed by the group for inclusion in the review. In all, this article summarizes and provides commentary on the potential clinical impact of 13 articles, 4 guidelines, and 3 meta-analyses covering topics including anticoagulant reversal, tenecteplase in acute ischemic stroke, guideline updates for heart failure and aortic aneurysm, magnesium in atrial fibrillation, sedation in mechanically ventilated patients and pain management strategies in the Emergency Department (ED), and tranexamic acid use in epistaxis and GI bleed.Copyright © 2023 Elsevier Inc. All rights reserved.

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