• Ji-dong Zuo, Zhen-guang Chen, Wei-bin Liu, and Min Tan.
• Department of Minimal Invasive Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China. zuojd@126.com
• Nan Fang Yi Ke Da Xue Xue Bao. 2009 Apr 1;29(4):794-7.

ObjectiveTo compare the therapeutic effects of video-assisted thoracoscopic extended thymectomy (VATET) and transsternal extended thymectomy (TET) for myasthenia gravis (MG).MethodThis study included 21 patients undergoing VATET through the "three holes" approach on the right chest and 32 undergoing TET with sternum dissection. The thymus was excised and the anterior mediastinum adipose tissue removed in both groups.ResultsVATET was associated with reduced intraoperative blood loss and longer operative time without the use of postoperative analgesics; very few patients were admitted into the intensive care unit (ICU), showing significant differences from the TET group (P<0.05). No significant difference was found between the two groups in tracheal tube removal time, length of stay in ICU, closed thoracic drainage removal time, and postoperative hospital stay, total hospital stay, postoperative complications, total hospitalization costs, or the rate of remission and improvement (P>0.05).ConclusionsCompared with TET, VATET requires only a small incision without leaving metal foreign body in the body, and the patients experience less postoperative pain and rapid recovery, with similar mid- and long-term clinical outcomes.

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