• Kailee M Pollock, Ronda Ambroziak, Chanda Mullen, Liz King, and Angela Barsa.
• Department of Pharmacy, Cleveland Clinic Akron General, Akron, OH.
• J. Cardiothorac. Vasc. Anesth. 2023 Aug 1; 37 (8): 140314091403-1409.

ObjectivesThe objective of this study was to assess the quality of pain control and outcomes in patients who underwent coronary artery bypass graft (CABG) over a period of 96 hours preimplementation of a cardiac enhanced recovery after surgery (C-ERAS) protocol compared with postimplementation.DesignSingle-center, retrospective cohort study.SettingCleveland Clinic Akron General Hospital.ParticipantsPatients ≥18 years of age who underwent CABG surgery and received perioperative pain management pre- and post-C-ERAS protocol implementation at admission to Cleveland Clinic Akron General Hospital.InterventionsA hospital C-ERAS protocol that included a multimodal analgesia approach to postoperative pain management.Measurements And Main ResultsThe primary outcome was the amount of opioid used measured in morphine milligram equivalents (MME) within 96 hours postoperatively. A total of 146 charts were reviewed, with 133 included (66 pre-C-ERAS and 67 post-C-ERAS). There was a significant reduction in median MMEs 96 hours postoperatively post-C-ERAS (98 [52-135] v 211 [130-290], p < 0.001). Additionally, a significant reduction in median MMEs was observed post-C-ERAS before (65 [43-100] v 129 [95-165], p < 0.001) and after (10 [0-40] v 68 [21-141], p < 0.001) chest tube removal and for the entire prescription at discharge (0 [0-109] v 90 [0-210], p = 0.005).ConclusionsImplementing a C-ERAS protocol within a CABG surgery patient population reduced the amount of MME.Copyright © 2023 Elsevier Inc. All rights reserved.

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