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- Claudia Angeli, Enrico Rejc, Maxwell Boakye, April Herrity, Samineh Mesbah, Charles Hubscher, Gail Forrest, and Susan Harkema.
- Department of Bioengineering, University of Louisville, Louisville, KY, USA; Kentucky Spinal Cord Injury Center, University of Louisville, Louisville, KY, USA; Frazier Rehabilitation Institute, University of Louisville Health, Louisville, KY, USA. Electronic address: claudia.angeli@louisville.edu.
- Neuromodulation. 2024 Jun 1; 27 (4): 645660645-660.
Study DesignThis is a report of methods and tools for selection of task and individual configurations targeted for voluntary movement, standing, stepping, blood pressure stabilization, and facilitation of bladder storage and emptying using tonic-interleaved excitation of the lumbosacral spinal cord.ObjectivesThis study aimed to present strategies used for selection of stimulation parameters for various motor and autonomic functions.ConclusionsTonic-interleaved functionally focused neuromodulation targets a myriad of consequences from spinal cord injury with surgical implantation of the epidural electrode at a single location. This approach indicates the sophistication of the human spinal cord circuitry and its important role in the regulation of motor and autonomic functions in humans.Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.
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