• Ali Mohamed Ali Ismail, Alshaymaa Shaaban Abd El-Azeim, and Hatem Fawzy Abd Elfatah Abo Saif.
• Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt. ali.mohamed@pt.cu.edu.eg.
• Ir J Med Sci. 2023 Dec 1; 192 (6): 315131613151-3161.

BackgroundLifestyle modification is a newly recommended complementary treatment for dry eye (DE) disorder.ObjectiveTo investigate the effect of a 6-month high-intensity interval aerobic exercise (HIIAE) (conducted 30 min, 3 times weekly) alone or combined with a caloric-restriction approach, the Mediterranean diet (MD), on DE parameters in obese hypertensive elderly.The Design, Settings, Participants, And InterventionThis is a randomized controlled trial included sixty obese hypertensive elderly with DE based on university-based hospital recruitment. Elderly were randomly assigned to the experimental group (n = 30 elderly received HIIAE plus MD) and control group (n = 30 elderly received only HIIAE). Besides anthropometry (abdominal circumference, body weight, and body mass index) and blood pressure (measured in systole and diastole), DE parameters (tear film break-up time, DE scoring system, ocular surface disability index questionnaire, Schirmer's test, and Oxford grading system) were evaluated.ResultsSignificant improvements in anthropometry, blood pressure, and DE parameters were higher in the experimental group than in the control group.ConclusionAging-related DE symptoms and signs can be prevented and/or treated with HIIAE alone or combined with MD in obese hypertensive elderly with DE disorder.© 2023. The Author(s).

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