• Internal medicine · Dec 2023

    Case Reports

    A Case of Primary Retroperitoneal Mucinous Cystadenocarcinoma during Long-term Administration of Infliximab for the Treatment of Crohn's Disease.

    • Yoshiki Morihisa, Shunji Urai, Hiroyoshi Iwagami, Masayuki Shimoyama, Shinya Ogino, Tomoko Terashita, Hiroki Morimura, Takuji Akamatsu, Yoshito Uenoyama, and Yukitaka Yamashita.
    • Department of Gastroenterology and Hepatology, Japanese Red Cross Wakayama Medical Center, Japan.
    • Intern. Med. 2023 Dec 15; 62 (24): 361936243619-3624.

    AbstractWe herein report a rare case of primary retroperitoneal mucinous cystadenocarcinoma (PRMC) in a 60-year-old man. The patient, who had been treated with infliximab for Crohn's disease of the colon for 13 years, was referred to our hospital for lower back pain. Contrast-enhanced computed tomography (CT) and magnetic resonance imaging revealed multiple cystic lesions in the right retroperitoneum, the calcification of the cyst, and bone lesions. Bone and CT-assisted biopsies of the retroperitoneal lesions revealed poorly differentiated adenocarcinoma. The patient was diagnosed with PRMC with bone metastases using immunohistochemical staining and positron emission tomography/CT.

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