• Amit Chopra, Peter Doelken, Kurt Hu, John T Huggins, and Marc A Judson.
• Department of Medicine, Pulmonary and Critical Care Medicine, Albany Medical Center, Albany, NY. Electronic address: chopraa1@amc.edu.
• Chest. 2023 Sep 1; 164 (3): 796805796-805.

AbstractPressure-dependent pneumothorax is a common clinical event, often occurring after pleural drainage in patients with visceral pleural restriction, partial lung resection, or lobar atelectasis from bronchoscopic lung volume reduction or an endobronchial obstruction. This type of pneumothorax and air leak is clinically inconsequential. Failure to appreciate the benign nature of such air leaks may result in unnecessary pleural procedures or prolonged hospital stay. This review suggests that identification of pressure-dependent pneumothorax is clinically important because the air leak that results is not related to a lung injury that requires repair but rather to a physiological consequence of a pressure gradient. A pressure-dependent pneumothorax occurs during pleural drainage in patients with lung-thoracic cavity shape/size mismatch. It is caused by an air leak related to a pressure gradient between the subpleural lung parenchyma and the pleural space. Pressure-dependent pneumothorax and air leak do not need any further pleural interventions.Copyright © 2023 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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