• Matthias Jacquet-Lagrèze, Christophe Saint-Jean, Thierry Bouët, Sébastien Reynaud, Martin Ruste, and Jean-Luc Fellahi.
• Service d'Anesthésie-Réanimation, Hospices Civils de Lyon, Hôpital Louis Pradel, Lyon, F-69500, France. matthias.jacquet-lagreze@chu-lyon.fr.
• J Clin Monit Comput. 2023 Oct 1; 37 (5): 140914121409-1412.

AbstractCapillary refill time (CRT) is an important indicator of peripheral perfusion with a strong prognostic value, but it is sensitive to environmental factors and numerous measurement methods are reported in the litterature. DiCARTECH has developed a device that assesses CRT. We sought to investigate the robustness of the device and the reproducibility of the algorithm in a bench and in-silico study. We used the video acquired from a previous clinical study on healthy volunteers. For the bench study, the measurement process was performed by a robotic system piloted by a computer that analyzed 250 times nine previously acquired videos. For the in-silico study, we used 222 videos to test the algorithm's robustness. We created 30 videos from each video with a large blind spot and used the "color jitter" function to create a hundred videos from each video. In the bench study, the coefficient of variation was 11% (95%CI: 9-13). The correlation with human-measured CRT was good (R2 = 0.91, P < 0.001). In the in-silico study, for the blind spotted video, the coefficient of variation was 13% (95%CI: 10-17). For the color-jitter modified video the coefficient of variation was 62% (95%CI: 55-70). We confirmed the ability of the DiCART™ II device to perform multiple measurements without mechanical or electronic dysfunction. The precision and reproducibility of the algorithm are compatible with the assessment of clinical small changes in CRT.© 2023. The Author(s), under exclusive licence to Springer Nature B.V.

9 keywords...

hide…