• Krishna Kumar Agrawaal, Sanjog Kandel, and Sudhan Devkota.
• Nephrology Unit, Department of Internal Medicine, Universal College of Medical Sciences, Bhairahawa, Rupandehi, Nepal.
• JNMA J Nepal Med Assoc. 2023 May 1; 61 (261): 446450446-450.

IntroductionChronic kidney disease is a major cause of mortality with a prevalence of 6%. Over the past half-century, hemodialysis has been the most preferred modality of treatment for sustaining the life of patients with end-stage kidney disease. Despite hemodialysis being freely available, achieving adequacy in hemodialysis is a challenging task. Inadequate dialysis is responsible for the high mortality. This study aimed to find out the mean value of the urea reduction ratio among patients undergoing hemodialysis at a tertiary care centre.MethodsThis was a descriptive cross-sectional study conducted from 15 January 2023 to 15 April 2023. Ethical approval was taken from Institutional Review Committee (Reference number: UCMS/IRC/044/23). Patients aged >18 years, undergoing maintenance hemodialysis and giving informed and written consent were included in the study. Urea reduction rate and single-pool Kt/V were estimated. Convenience sampling method was used.ResultsAmong 100 patients, the mean urea reduction ratio among the study population was 25.24±15.59%. Males represented 62 (62%) of the study population. The mean age was 47.9±14.74 years. Hypertension and Diabetes mellitus was found to be the leading cause of end-stage kidney disease with 61 (61%) and 27 (27%) respectively. The mean value of spKT/V was 0.73±0.162.ConclusionsThe mean urea reduction ratio was found to be lower than the other studies done in similar settings.Keywordschronic kidney disease; dialysis; hemodialysis.

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