• Ming-Tsung Lee, Shau-Huai Fu, Chih-Cheng Hsu, Ho-Min Chen, Jou-Wei Lin, Keh-Sung Tsai, Jawl-Shan Hwang, Sheng-Chieh Lin, Chih-Hsing Wu, and Chen-Yu Wang.
• National Center for Geriatrics and Welfare Research, National Health Research Institutes, Yunlin, Taiwan; Department of Nursing, Hungkuang University, Taichung, Taiwan.
• J Formos Med Assoc. 2023 Jan 1; 122 Suppl 1: S21S35S21-S35.

BackgroundOsteoporosis increases the fracture and mortality risk of patients and has a higher disease burden than some cancers. Therefore, global concerns regarding the prevention and treatment of osteoporosis have been raised. However, fast-aging Taiwan lacks national epidemiological data on osteoporosis in recent years. We aimed to establish and update epidemiological data on osteoporosis by analyzing national data from 2008 to 2019.MethodsWe estimated the prevalence and incidence of osteoporosis in patients aged ≥50 years based on claims data from Taiwan's National Health Insurance database from 2008 to 2019. We also analyzed the key parameters of fracture care (anti-osteoporosis medication use, bone mineral density examination rate, and length of hospital stay) to understand the secular trend of management and related clinical outcomes (imminent refracture rate and mortality).ResultsThe number of prevalent osteoporosis increased from 2008 to 2015 and remained constant until 2019; however, the age-standardized prevalence and incidence rates declined from 2008 to 2019 (3.77%-2.91% and 2.08%-1.02%, respectively). The overall incidence rates of hip and spine fractures decreased significantly by 34% and 27%, respectively. For patients with hip and spine fractures, the immanent refracture rates were 8.5% and 12.9% and the 1-year mortality rate remained stable at approximately 15% and 6%, respectively.ConclusionThe age-standardized prevalence and incidence rates decreased remarkably from 2008 to 2019, while the number of prevalent osteoporosis remained steady. Patients with hip fractures encountered a high 1-year mortality rate, while the risk of imminent refracture was notable for patients with spine fractures.Copyright © 2023. Published by Elsevier B.V.

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