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- Hideo Kihara, Shingo Konno, Takafumi Uchi, Jun Isonishi, Hideki Sugimoto, and Toshiki Fujioka.
- Department of Neurology, Toho University Ohashi Medical Center, Japan.
- Intern. Med. 2024 Jan 15; 63 (2): 319322319-322.
AbstractEncephalitis caused by antibodies targeting the leucine-rich glioma-inactivated 1 protein receptor, which belongs to the anti-voltage-gated potassium channel receptor complex, is characterized by hyponatremia, progressive cognitive impairment, seizures, and psychiatric disorders. The patient initially presented with faciobrachial dystonic seizures and subsequently developed encephalopathy. Brain magnetic resonance imaging revealed atypical unilateral hyperintense signals in the cerebral cortex and white matter. Intravenous corticosteroid pulse therapy effectively improved faciobrachial dystonic seizures and brain lesions.
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