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Case Reports
Primary Cytomegalovirus Pneumonia Successfully Treated with Corticosteroid Therapy and Valganciclovir.
- Kyoko Gocho, Aya Yamashita, Noboru Iizuka, Kenya Sato, Keisuke Imasaka, Nobuyuki Hamanaka, and Tokuhiro Kimura.
- Department of Respiratory Medicine, Saiseikai Yokohamashi Tobu Hospital, Japan.
- Intern. Med. 2024 Jan 15; 63 (2): 271276271-276.
AbstractCytomegalovirus infection is typically asymptomatic in immunocompetent individuals. A 26-year-old woman was admitted to our hospital with a fever and breathlessness. Chest computed tomography (CT) revealed bilateral diffuse reticulation and nodules. Laboratory investigations showed atypical lymphocytosis and increased transaminases. She was treated with corticosteroid pulse therapy because of acute lung injury, and her clinical condition improved. Based on the presence of cytomegalovirus antibodies, antigen, and polymerase chain reaction findings, she was diagnosed with primary cytomegalovirus pneumonia and treated with valganciclovir. Primary cytomegalovirus pneumonia is very rare in immunocompetent individuals. The efficacy of corticosteroid and valganciclovir against cytomegalovirus pneumonia in this patient is noteworthy.
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