• Reg Anesth Pain Med · Oct 2023

    Case Reports

    Stellate ganglion block catheter for paroxysmal sympathetic hyperactivity: calming the 'neuro-storm'.

    • Man-Cheung Lee, Andrew Bartuska, Jeffrey Chen, Richard K Kim, Safwan Jaradeh, and Fred Mihm.
    • Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California, USA.
    • Reg Anesth Pain Med. 2023 Oct 1; 48 (10): 522525522-525.

    BackgroundParoxysmal sympathetic hyperactivity (PSH) is an autonomic disorder affecting patients with severe acquired brain injury characterized by intermittent sympathetic discharges with limited therapeutic options. We hypothesized that the PSH pathophysiology could be interrupted via stellate ganglion blockade (SGB).Case PresentationA patient with PSH after midbrain hemorrhage followed by hydrocephalus obtained near-complete resolution of sympathetic events for 140 days after SGB.ConclusionSGB is a promising therapy for PSH, overcoming the limitations of systemic medications and may serve to recalibrate aberrant autonomic states.© American Society of Regional Anesthesia & Pain Medicine 2023. No commercial re-use. See rights and permissions. Published by BMJ.

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