• Br J Anaesth · Aug 2023

    Editorial Comment

    Reversal of neuromuscular block: what are the costs?

    • Karsten Bartels, Ana Fernandez-Bustamante, and Vidal MeloMarcos FMFDepartment of Anesthesiology, Columbia University, New York, NY, USA. Electronic address: mv2869@cumc.columbia.edu..
    • Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, USA; Outcomes Research Consortium, Cleveland, OH, USA.
    • Br J Anaesth. 2023 Aug 1; 131 (2): 202204202-204.

    AbstractPatients requiring neuromuscular block for anaesthesia have a higher risk of adverse postoperative outcomes. The choice of reversal drug and its corresponding dose is critical for improving clinical outcomes. Although drug costs are higher for sugammadex relative to neostigmine, additional factors need to be considered when choosing one drug over the other. New data from a recent study in the British Journal of Anaesthesia indicate cost advantages for sugammadex in low-risk and ambulatory patients, but for neostigmine in high-risk patients. These findings highlight the need to take local and temporal factors into consideration in addition to clinical effectiveness when performing cost analyses for administrative decision-making.Copyright © 2023 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

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