• Hyun-Gyu Kim, Ji-Hee Han, Ji-Yoon Kwak, Han Kyu Jeon, Sang-Soo Lee, Hyun Jin Kim, Seul Ki Song, Byoung-Kuk Na, and Ra-Ri Cha.
• Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea.
• Medicine (Baltimore). 2023 Jun 2; 102 (22): e34000e34000.

RationaleClinostomum complanatum is a laryngeal fluke whose hosts include birds and mammals.[1] In humans, infection occurs accidentally during the consumption of raw freshwater fish.[1,2].Patient ConcernsA 59-year-old female presented to our hospital with throat pain and globus sensation. The patient had been prescribed Proton Pump Inibitor for 3 weeks at another hospital. The patient continued the medication, but the discomfort persisted, and she was admitted to our hospital for further examination. The patient had eaten raw fish 24 days before, and the symptoms occurred after eating the raw fish. Endoscopy under sedation showed a fluke, with an approximate length of 8.0 mm and width of 3.2 mm, on the interaryepiglottic fold, with active motility on the mucosa.Diagnosis InterventionsIt was extracted from the larynx using biopsy forceps and identified as C complanatum.OutcomesAfter the fluke was removed, symptoms improved, and the patient was discharged. The globus symptoms completely resolved at the last follow-up visit.LessonsTo the best of our knowledge, this is an endoscopically diagnosed and treated case of human infection by C complanatum in Korea after the longest period of infection. This suggests that C complanatum can survive for up to 3 weeks or more in the gastrointestinal tract. Endoscopy is a useful tool for the diagnosis and treatment of patients with atypical extraesophageal symptoms who do not respond to Proton Pump Inibitors.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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