• Internal medicine · Jan 2024

    Case Reports

    Chronic Pulmonary Aspergillosis Caused by Aspergillus tubingensis Diagnosed by a Bronchoscopic Biopsy.

    • Ryo Sekiguchi, Keita Takeda, Junko Suzuki, Yu Enomoto, Masashi Kitani, Osamu Narumoto, Hiroyuki Tashimo, Akira Yamane, Hideaki Nagai, Akira Watanabe, Katsuhiko Kamei, and Hirotoshi Matsui.
    • Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan.
    • Intern. Med. 2024 Jan 15; 63 (2): 289292289-292.

    AbstractWe herein report a case of chronic pulmonary aspergillosis (CPA) caused by Aspergillus tubingensis diagnosed by a bronchoscopic biopsy with negative serological and sputum culture findings. A 66-year-old man was referred for the assessment of a pulmonary cavity. Computed tomography showed a thick-walled cavity in the upper right pulmonary lobe. Serum β-D glucan, Aspergillus galactomannan, and Aspergillus antibody tests were negative. Aspergillus species were not detected in the sputum. Culture and pathological specimens were obtained from the mass by bronchoscopy. Microscopic examination findings were consistent with Aspergillus niger complex morphologically and identified as Aspergillus tubingensis through DNA sequencing. The patient was diagnosed with chronic pulmonary aspergillosis.

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