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- Michael Perlmutter, Mark Price, Kathryn Kothari, Zubaid Rafique, Kelly Rogers Keene, Xavier De La Rosa, Elizabeth Weinstein, and Casey Patrick.
- Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota.
- Prehosp Emerg Care. 2023 Jan 1; 27 (7): 920926920-926.
AbstractWe report the initial six pediatric patients treated with ketamine for benzodiazepine-resistant status epilepticus in an urban, ground-based emergency medical services (EMS) system. Evidence for ketamine as a second-line agent for both adult and pediatric refractory seizure activity in the hospital setting has increased over the past decade. The availability of an inexpensive and familiar second-line prehospital anti-epileptic drug option is extremely desirable. We believe these initial data demonstrate promising seizure control effects without significant respiratory depression, indicating a potential role for ketamine in the EMS treatment of pediatric benzodiazepine-refractory seizures.
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