• Ana Ligia Gutiérrez-Solis, Oscar Daniel Pacheco-Can, Hayde Sara Leticia Vázquez-Segura, Alfredo Geovanny Pech-Aguilar, Carlos David Franco-González, Azalia Avila-Nava, and Roberto Lugo.
• Hospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, México.
• Medicine (Baltimore). 2023 Jun 9; 102 (23): e33915e33915.

BackgroundGastric cancer (GC) is one of the most frequent cancer types in Mexico. The primary method used as a treatment is surgical resection. The role of surgery in increasing survival is controversial. This study aimed to determine whether surgical resection increases the survival of patients with GC in a Mexican population.MethodsA systematic review of literature searches (Evidence-based MEDLINE/PubMed, Web of Science, Cochrane Library, and SciELO) and meta-analysis were performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis criteria. The published articles from 2000 to the current time were divided into cross-sectional and randomized studies. The inclusion criteria were survival, surgical resections, patients treated in Mexico, and primary GC. The effect estimation was calculated using the risk ratio (RR). The random-effects model and a confidence interval (CI) of 95% were used.ResultsThe RR of the pooled studies was 1.09 (95% CI, 0.71-1.67). RR of 0.82 (95% CI, 0.63-1.07) was obtained in cross-sectional studies, and randomized studies showed a RR of 2.08 (95% CI, 0.25-17.07).ConclusionThis work is the first systematic study that assesses the role of surgery on the survival of patients with GC in the Mexican population, the results showed that surgical resection did not improve survival in patients with GC.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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