• Joshua Wilcox, Simon Redwood, and Tiffany Patterson.
• Cardiovascular Department, Guy's and St. Thomas' NHS Foundation Trust, UK. Electronic address: Joshua.wilcox@gstt.nhs.uk.
• Resuscitation. 2023 Aug 1; 189: 109865109865.

AbstractThere are wide regional variations in outcome following resuscitated out of hospital cardiac arrest. These geographical differences appear to be due to hospital infrastructure and provider experience rather than baseline characteristics. It is proposed that post-arrest care be delivered in a systematic fashion by concentrating services in Cardiac Arrest Centres, with greater provider experience, 24-hour access to diagnostics, and specialist treatment to minimise the impact of ischaemia-reperfusion injury and treat the causative pathology. These cardiac arrest centres would provide access to targeted critical care, acute cardiac care, radiology services and appropriate neuro-prognostication. However implementation of cardiac arrest networks with specialist receiving hospitals is complex and requires alignment of pre-hospital care services with those delivered in hospital. Furthermore there are no randomised trial data currently supporting pre-hospital delivery to a Cardiac Arrest Centre and definitions are heterogeneous. In this review article, we propose a universal definition of a Cardiac Arrest Centre and review the current observational data evidence and the potential impact of the ARREST trial.Crown Copyright © 2023. Published by Elsevier B.V. All rights reserved.

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