• Monaldi Arch Chest Dis · Jun 1994

    Review

    Neuroendocrine cells and airway wall remodelling in chronic airflow obstruction: a perspective.

    • S M Aguayo.
    • Pulmonary Disease Section, Atlanta Department of Veterans Affairs Medical Center, Decatur, GA 30033.
    • Monaldi Arch Chest Dis. 1994 Jun 1;49(3):243-8.

    AbstractRecent investigations suggest that airway wall remodelling and chronic airflow obstruction are almost always associated with increased pulmonary neuroendocrine (NE) cells and increased levels of bombesin-like peptides (BLPs), particularly among cigarette smokers. In contrast, most normal subjects and even smokers who do not develop airflow obstruction do not exhibit such airway wall remodelling, increased NE cells, or increased BLP levels. The hypothesis forwarded, therefore, is that NE cells and BLPs may play a role in the pathogenesis of airway wall remodelling and chronic airflow obstruction.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…