• Smit Shah, Eris Spirollari, Christina Ng, Kevin Cordeiro, Kevin Clare, Bridget Nolan, Alexandria F Naftchi, Austin B Carpenter, Jose F Dominguez, Ian Kaplan, Brittany Bass, Emily Harper, Jon Rosenberg, Dipak Chandy, Stephan A Mayer, Kartik Prabhakaran, Arthur Wang, Chirag D Gandhi, and Fawaz Al-Mufti.
• Department of Neurology, University of South Carolina/PRISMA Health Richland, Columbia, SC, United States of America.
• J Crit Care. 2023 Dec 1; 78: 154357154357.

PurposeRespiratory failure following mechanical thrombectomy (MT) for acute ischemic stroke (AIS) is a known complication, and requirement of tracheostomy is associated with worse outcomes. Our objective is to evaluate characteristics associated with tracheostomy timing in AIS patients treated with MT.MethodsThe National Inpatient Sample was queried for adult patients treated with MT for AIS from 2016 to 2019. Baseline demographic characteristics, comorbidities, and inpatient outcomes were analyzed for associations in patients who received tracheostomy. Timing of early tracheostomy (ETR) was defined as placement before day 8 of hospital stay.ResultsOf 3505 AIS-MT patients who received tracheostomy, 915 (26.1%) underwent ETR. Patients who underwent ETR had shorter length of stay (LOS) (25.39 days vs 32.43 days, p < 0.001) and lower total hospital charges ($483,472.07 vs $612,362.86, p < 0.001). ETR did not confer a mortality benefit but was associated with less acute kidney injury (OR, 0.697; p = 0.013), pneumonia (OR, 0.449; p < 0.001), and sepsis (OR, 0.536; p = 0.002).ConclusionAn expected increase in complications and healthcare resource utilization is seen in AIS-MT patients receiving tracheostomy, likely reflecting the severity of patients' post-stroke neurologic injury. Among these high-risk patients, ETR was predictive of shorter LOS and fewer complications.Copyright © 2023 Elsevier Inc. All rights reserved.

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