• Atencion primaria · Oct 2023

    [Management from Primary Care of monkeypox infection (MPOX) in humans].

    • Arranz IzquierdoJavierJInstituto de Investigación Sanitaria de Illes Balears (Idisba), Illes Balears, España; Centro de Salud Escola Graduada, Ibsalut, Palma de Mallorca, Illes Balears, España; Grupo de trabajo de enfermedades infecciosas de SemFYC, Madri, Molero GarcíaJosé MaríaJMGrupo de trabajo de enfermedades infecciosas de SemFYC, Madrid, España; Centro de Salud San Andrés, DA Centro (SERMAS), Madrid, España. Electronic address: jmolerog@gmil.com., and Gutiérrez PérezMaría IsabelMIGrupo de trabajo de enfermedades infecciosas de SemFYC, Madrid, España; Centro de Salud Delicias I (GAP Oeste), Valladolid, España..
    • Instituto de Investigación Sanitaria de Illes Balears (Idisba), Illes Balears, España; Centro de Salud Escola Graduada, Ibsalut, Palma de Mallorca, Illes Balears, España; Grupo de trabajo de enfermedades infecciosas de SemFYC, Madrid, España.
    • Aten Primaria. 2023 Oct 1; 55 (10): 102680102680.

    AbstractMonkeypox (MPOX) is a viral zoonosis endemic in West or Central African countries that is sporadically exported to another area. In May 2022, a global outbreak of MPOX smallpox began to occur in several countries in Europe and North America. Most of the reported cases are identified at the outpatient level and mainly affect men who have sex with men (MSM). Transmission is by close contact with lesions, body fluids, respiratory secretions or contaminated material from an infected person or animal. The clinical picture is similar to human smallpox, with less severity. Mild, self-limiting skin involvement predominates after 2-4 weeks. In MSM, atypical skin lesions appear due to the mode of infection. Severe forms or complications may appear in certain risk groups. The case fatality rate is 3%-6% depending on the clade responsible. The diagnosis of suspicion is confirmed by detection of the virus from exudates of lesions or scabs, with nucleic acid amplification techniques by conventional or real-time PCR. Clinical management in most cases is performed in primary care (PC), by monitoring the main symptoms. Between 5-10% require hospital management and there are some specific antiviral treatment options. Human smallpox vaccines protect against MPOX and are used as pre- and post-exposure prophylaxis for persons at risk. Measures to reduce exposure to the virus are the main MPOX prevention strategy. In addition, the role of the family physician is key to controlling the spread of MPOX through active surveillance and early diagnosis of the disease.Copyright © 2023 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.

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