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- Kenichi Kishimoto, Kotaro Shibagaki, Asuka Araki, Kotaro Murakami, Yusuke Takahashi, Satoshi Kotani, Akihiko Oka, Tomotaka Yazaki, Nobuhiko Fukuba, Yoshiyuki Mishima, Naoki Oshima, Kousaku Kawashima, Norihisa Ishimura, Kyuichi Kadota, and Shunji Ishihara.
- Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan.
- Intern. Med. 2024 Feb 1; 63 (3): 373378373-378.
AbstractA 59-year-old man underwent submandibular gland excision for salivary duct carcinoma (SDC). One year later, esophagogastroduodenoscopy indicated gastric diffuse mucosal thickening with luminal contraction, mimicking scirrhous gastric carcinoma. Biopsy specimens showed dense proliferation of neoplastic cells expressing androgen receptor and human epidermal growth factor 2, indicating SDC. Gastric diffuse infiltrative metastasis is generally characteristic of gastric metastasis from invasive ductal carcinoma, which shows histologic features similar to SDC. This is the first known report of gastric diffusely infiltrating metastasis in an SDC patient. Rapidly progressing, diffuse gastric wall thickening should also be considered indicative of salivary tumor-associated gastric metastasis.
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