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- Yurika Hada, Akane Yamada, Takuya Kobayashi, Takuma Sugiyama, Kota Ishii, Kaoru Takase, Noe Takakubo, Kyoko Nagaoka, Shigeru Karasawa, Wataru Kameda, Kenichi Ishizawa, and Shinji Susa.
- Department of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Japan.
- Intern. Med. 2024 Feb 1; 63 (3): 419423419-423.
AbstractBilateral adrenal infarction is an extremely rare disease, and it has been reported that some coagulation abnormalities, including essential thrombocythemia (ET), exist in the background. We herein report a 76-year-old patient in whom the platelet count had been in the normal range at the onset of adrenal infarction but subsequently increased to 102×104/μL at 7 months later, leading to the diagnosis of JAK2V617F-positive ET. As the presence of the JAK2V617F mutation increases the risk of thrombosis, Janus kinase 2 (JAK2) genetic testing should be considered in some cases of nonspecific unknown thrombosis, even if there are no obvious hematological findings, such as clonal hematopoiesis of indeterminate potential (CHIP).
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