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- Yuta Yonezawa, Kenichi Koga, Yoshiaki Higashi, Masako Hasebe, Chiho Fukushima, Chiaki Omiya, Keisuke Nishioka, and Kensei Yahata.
- Department of Nephrology, Osaka Red Cross Hospital, Japan.
- Intern. Med. 2024 Feb 15; 63 (4): 527532527-532.
AbstractA 33-year-old woman developed hypertensive emergency (268/168 mmHg) with renal failure and hypertensive retinopathy. Four hours after the initiation of antihypertensive therapy with the continuous infusion of nicardipine, her blood pressure (BP) decreased to 168/84 mmHg; however, the patient developed blindness. She was diagnosed with posterior ischemic optic neuropathy (PION). Her BP was maintained at approximately 175/90 mmHg until her vision improved. Olmesartan was initiated on day 13, and her BP decreased to approximately 135/95 mmHg without the re-exacerbation of vision loss. Although the prognosis of PION is poor, its early diagnosis and gradual antihypertensive therapy may help preserve the patient's vision.
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