• M Lourdes Suarez-Roa, Luz-Elena Espinosa de Los Monteros-Perez, Juan-Francisco Galán-Herrera, Lorena Hernández-Ramirez, and Abelardo A Meneses-García.
• Department of Pathology, National Cancer Institute, Mexico City, Mexico; Clinical Research Division, General Hospital "Dr. Manuel Gea Gonzalez", Mexico City, Mexico. Electronic address: lusuroa@gmail.com.
• Med Clin (Barc). 2023 Sep 29; 161 (6): 238242238-242.

ObjectiveTo determine the presence of human papillomavirus (HPV) in the oral mucosa of blood donors (BD) and risk factors associated with HPV and oral cancer.Materials And MethodsProspective cross-sectional study, population matched to BD from the National Cancer Institute, Mexico for HPV identification in oral cytological samples using the CLART® Human Papillomavirus 2 Kit (35 genotypes) and risk factors.ResultsOf 352 BD with signed informed consent, 285 were selected by simple randomization. The prevalence of oral HPV was 17.5% (95% CI 13-21.9%), the genotype was identified in 13 cases, with a total of 16 genotypes (10 high-risk), the most common being 16 and 84. Five cases had multiple infections, three with at least one high-risk type. Associations were found for marital status (OR 3.3) and educational level (OR-1.9).ConclusionsThe percentage of HPV-positive cases in blood donors with no risk practices was similar to that found in Spanish-speaking population studies in which at least one risk practice was described. The presence of other genotypes with high oncogenic risk and multitype infection, described as a marker of persistence of HPV infection, is highlighted.Copyright © 2023 Elsevier España, S.L.U. All rights reserved.

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