• Dtsch. Med. Wochenschr. · Jul 2023

    [Drug toxic hepatopathy - an underestimated danger].

    • Elke Roeb.
    • Dtsch. Med. Wochenschr. 2023 Jul 1; 148 (13): 828835828-835.

    AbstractDrug-induced toxic hepatopathies and drug-induced liver injury, DILI, are characterized by a variety of clinical manifestations and therefore represent a significant diagnostic challenge. This article shows how DILI is diagnosed and what therapy options exist. Current special cases of DILI genesis are also discussed (DOACs, IBD drugs, tyrosine kinase inhibitors). These newer substances and corresponding hepatotoxic effects are not yet fully understood. The internationally recognized and online available RUCAM score (Roussel Uclaf Causality Assessment Method) helps to assess the probability of drug-related toxic liver damage.Thieme. All rights reserved.

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