• J Francisco López, Mario I Fernández, and Fernando Coz.
• Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
• Rev Med Chil. 2022 Oct 1; 150 (10): 137013791370-1379.

BackgroundProstate cancer is the tumor with the highest incidence among men and one of Chile's leading causes of death.AimTo analyze temporal trends in prostate cancer mortality in Chile.Material And MethodsMortality rates in Chile for the period between 1955 and 2019 were calculated. The number of deaths was obtained from the national demographic yearbooks and the Ministery of Health mortality registries. Population estimates from the demographic center of the Economic Commission for Latin America and the Caribbean of the United Nations were used. Chilean census population of 2017 was used as reference to calculate adjusted rates. Trends were analyzed using a join point regression.ResultsCrude mortality rates of prostatic cancer increased between 1995 and 2012 in three different phases, namely between 1955 and 1989 with a 2.7% annual increase, between 1989 and 1996 at a 6.8% annual rate, and between 1996 to 2012 with a 2.8% annual increase. From 2012 the rate remained stable. Adjusted mortality rates increased slowly at a 1.7% rate from 1955 to 1993, accelerating between 1993 and 1996, when they increased 12.1% per year. From 1996 onwards there was a significant decrease in mortality at a 1.2% annual rate. This decrease was significant and observed within all age groups but more importantly at older ages.ConclusionsProstate cancer mortality in Chile has decreased significantly during the last two decades, like that observed in developed nations.

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