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Revista médica de Chile · Oct 2022
Case Reports[Fecal microbiota transplantation in an older patient with Clostridioides difficile recurrent infection. Report of one case].
- Paulina Núñez, Rodrigo Quera, Christian Von Muhlenbrock, Alexandra Concha, and Katherine Flores.
- Programa de Enfermedad Inflamatoria Intestinal, Centro de Enfermedades Digestivas, Clínica Universidad de los Andes, Santiago, Chile.
- Rev Med Chil. 2022 Oct 1; 150 (10): 139614001396-1400.
AbstractClostridioides difficile infection (CDI) is a major public health problem and responsible for significant morbidity and mortality. Eighty percent of CDIs occur in adults older than 65 years of age due to a decreased gastrointestinal microbial diversity, immunosenescence and frailty. Thus, the most reported risk factor for recurrent CDI is older age since nearly 60% of cases occur in individuals aged ≥ 65 years. Fecal microbiota transplantation (FMT) is a highly cost-effective alternative to antibiotic treatment for patients with recurrent CDI. We report a 75-year-old male with recurrent CDI, who received a FMT after several unsuccessful antimicrobial treatments. He had a satisfactory evolution after the procedure and remained without diarrhea during the ensuing five months.
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