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Revista médica de Chile · Sep 2022
[Evolution and prognostic factors associated with mortality in older adults hospitalized for COVID-19].
- Cecilia Carvacho, Nadia Vargas Donoso, René Medina, César Gallegos, Raffaela Carvacho, Olga Uauy, M Ignacia Ward, Constanza Márquez-Espinoza, Juan Pablo Sanhueza Quiñeman, and Homero Gac.
- Servicio de Kinesiología, Clínica San Carlos, Red de Salud UC-Christus, Santiago, Chile.
- Rev Med Chil. 2022 Sep 1; 150 (9): 114511511145-1151.
BackgroundSARS-CoV-2 affects all age groups, but higher mortality rates are recorded in older people, men and with comorbidities, mainly hypertension, diabetes and obesity.AimTo describe the main clinical characteristics, evolution and prognostic factors for death in older patients hospitalized for COVID-19.Materials And MethodsRetrospective analysis of 128 patients aged 73 years, 66% men, hospitalized at a clinical hospital, with a diagnosis of COVID-19, admitted from May 1 to August 1, 2020. Data were collected from the clinical records, a description of the study population was made, and a univariate analysis and logistic regression were performed.ResultsSeventy-two percent of patients had two or more comorbidities, mainly arterial hypertension in 66%, diabetes mellitus in 34% and cardiovascular disease in 19%. Forty-one percent were admitted to intensive care and 31% were connected to mechanical ventilation. In-hospital mortality was 26.6%. A multivariate analysis was performed in two blocks, finding in the first that arterial hypertension and older age significantly predict mortality. However, when previous institutionalization and immuno-suppression were included as variables in the second block, age ceased to be a significant predictor.ConclusionsPrognostic factors associated with death in this age group are arterial hypertension and previous institutionalization.
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