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Internal medicine journal · Jul 2023
Case ReportsInteraction between ferric carboxymaltose and denosumab causing severe hypocalcaemia and hypophosphataemia in a patient without chronic kidney disease.
- Jaidyn Muhandiramge, Vivian Lee, Monica Tran, and Lannie Ho.
- School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
- Intern Med J. 2023 Jul 1; 53 (7): 127312761273-1276.
AbstractCoadministration of ferric carboxymaltose and denosumab may cause hypocalcaemia and hypophosphataemia; however, this interaction is not well-described in the literature and has typically been described in patients with chronic kidney disease (CKD). We present a case of this interaction in a patient without preexisting CKD. We suggest the use of alternative iron preparations and an interval of at least 4 weeks between administrations.© 2023 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.
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