• Hwa-Young Jang, Won-Jung Shin, Daun Jeong, Jihun Baek, and In-Kyung Song.
• Department of Anesthesiology and Pain Medicine, Asan Medical Center, Seoul, Republic of Korea.
• J. Cardiothorac. Vasc. Anesth. 2023 Oct 1; 37 (10): 202020262020-2026.

ObjectivesTo identify the association between preoperative low muscle mass and early postoperative outcomes in pediatric patients undergoing total correction of tetralogy of Fallot (TOF).DesignA retrospective cohort study.SettingA single university hospital in Seoul, South Korea.ParticipantsPediatric patients (≤3 years) who underwent total correction of TOF between May 2008 and February 2018.InterventionsNone.Measurements And Main ResultsCross-sectional areas of the pectoralis and erector spinae muscles were measured using preoperative chest computed tomography (CT) scans, and adjusted to body surface area to define muscle mass index. The patients were divided into sarcopenia, presarcopenia, and no sarcopenia groups based on cutoff values determined using the mean and SD of the muscle mass index in the third z-weight quintile. Of a total of 330 patients included in the final analysis, 13 were associated with the sarcopenia group, 57 in the presarcopenia group, and 260 in the no sarcopenia group. The sarcopenia group exhibited a higher incidence of major adverse events than the presarcopenia and no sarcopenia groups, respectively (38% v 25% v 18%; p = 0.033). Logistic regression analyses revealed that only younger age at the time of surgery was significantly associated with major adverse events (odds ratio 0.82; 95% CI 0.72-0.94, p = 0.003).ConclusionsThe incidence of sarcopenia, as assessed by preoperative chest CT, was low in pediatric patients undergoing total correction of TOF, and preoperative sarcopenia did not predict early postoperative major adverse events.Copyright © 2023 Elsevier Inc. All rights reserved.

20 keywords...

hide…