• Dtsch Arztebl Int · Sep 2023

    The Treatment of Patients With an Unruptured Abdominal Aortic Aneurysm and a Concomitant Malignancy-Short- and Long-Term Results.

    • Jasmin Epple, Neelam Lingwal, Thomas Schmitz-Rixen, Dittmar Böckler, Reinhart T Grundmann, and DIGG gGmbH.
    • Department of Vascular and Endovascular Surgery, University Hospital, Goethe- University, Frankfurt am Main, Germany; Department of Biostatistics and Mathematical Modeling, University Hospital, Goethe-University, Frankfurt am Main, Germany; Goethe-University, Frankfurt am Main, Germany; Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Germany; German Institute for Health Research in Vascular Medicine (DIGG gGmbH), Berlin, Germany.
    • Dtsch Arztebl Int. 2023 Sep 4; 120 (35-36): 589594589-594.

    BackgroundHaving cancer adversely effects the outcome of treatment for an unruptured abdominal aortic aneurysm (AAA).MethodsA retrospective secondary analysis was performed on the basis of anonymized data from AOK, a German nationwide statutory healthinsurance carrier. Data were evaluated from all of the 20 683 patients who underwent either endovascular (EVAR, 15 792) or open surgical (OAR, 4891) treatment for an unruptured AAA in the years 2010-2016. It was determined in each case whether the patient had a known cancer at the time of the procedure to treat AAA. The analysis concerned patient characteristics, periprocedural complications, and survival after the procedure up to 31 December 2018.Results18 222 patients were free of cancer. In accordance with the known 6:1 sex ratio of AAA, 85.3% of the cancer-free patients and 92.8% of those with cancer were men. At the time of their AAA procedure, 1398 had cancer of the intestine (n = 318), lung (n = 301), prostate (n = 380), or bladder or ureter (n = 399). One-year survival after the AAA procedure was 91.5% in cancer-free patients and 84%, 74.4%, 85.8%, and 85.5% in the patients with the respective types of cancer just mentioned. Having cancer was a significant risk factor for periprocedural mortality (OR 1.326, p = 0.041) and for long-term survival (HR 1.515; p < 0.001).ConclusionHaving cancer is a risk factor for periprocedural mortality and long-term survival in patients undergoing treatment for an unruptured AAA. This implies that the indications for surgery should be considered with care, particularly in patients with lung cancer, whose 5-year survival rate is only 37.2%.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…