• Michael Bonares, Kalli Stillos, Lise Huynh, and Debbie Selby.
• Division of Palliative Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
• Palliat Med. 2023 Sep 1; 37 (8): 124112511241-1251.

BackgroundPatients with and without cancer are frequently hospitalized, and have specialist palliative care needs. In-hospital mortality can serve as a quality indicator of acute care. Trends in acute care outcomes have not previously been evaluated in patients with confirmed specialist palliative care needs or between diagnostic groups.AimTo compare trends in discharge location between hospitalized patients with and without cancer who received specialist palliative care.DesignRetrospective cohort study. Association between diagnosis (cancer, non-cancer) and in-hospital mortality was assessed using multivariable logistic regression, controlling for demographic, clinical, and admission-specific information.Setting/ParticipantsPatients who received specialist palliative care at an academic tertiary hospital in Toronto, Canada from 2013 to 2019.ResultsThe cohort comprised 6846 patients, 5024 with and 1822 without cancer. A higher proportion of patients without cancer had a Palliative Performance Scale score <30%, anticipated prognosis of <1 month, and were referred for end-of-life care (all p < 0.001). The adjusted odds of dying in hospital was 1.24-times higher among patients without cancer (95% CI: 1.05-1.46; p = 0.011). Though the proportion of patients without cancer who died in hospital decreased by 8.4% from 2013 to 2019, this proportion (41.2%) remained substantially higher compared to patients with cancer (14.0%) in 2019.ConclusionsHospitalized patients without cancer were referred to specialist palliative care at a lower functional status, a poorer anticipated prognosis, and more likely for end-of-life care; and were more likely to die in hospital. Future studies are required to determine whether a proportion of hospital deaths in patients without cancer represent goal-discordant end-of-life care.

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