• Erkan Şimşek, Şükrü Yıldız, Sema Karakaş, Sadık Gündüz, Özge Akdeniz Yıldız, İsa Aykut Özdemir, and Levent Yaşar.
• University of Health Sciences Turkey, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology - Istanbul, Turkey.
• Rev Assoc Med Bras (1992). 2023 Jan 1; 69 (7): e20221720e20221720.

ObjectiveOur goal was to contrast the prognoses of patients with endometrial cancer who had adenomyosis against those that did not.MethodsAll patients who had received surgical staging for hysterectomy-based endometrial cancer had their medical data retrospectively examined. The analysis covered 397 patients, who were split into two groups depending on the presence of adenomyosis. Comparisons were made between patients covering type of surgery, histopathology, endometrial cancer stage, lymphovascular space invasion, presence of biochemical or histochemical markers, adjuvant therapy, presence of adenomyosis in the myometrial wall, and outcomes in terms of overall survival and disease-free survival.ResultsThere is no statistically significant difference in the 5-year disease-free survival or overall survival rates between endometrial cancer patients with and without adenomyosis. This is based on comparisons of tumor stage, tumor diameter, histological type and grade of tumor, myometrial invasion, lymphovascular space invasion, and biochemical markers that affect the course of the disease. The median follow-up times were 61 months for the adenomyosis-positive group and 56 months for the group without adenomyosis.ConclusionCoexisting adenomyosis in endometrial cancer has no bearing on survival rates and is not a prognostic factor.

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