• Internal medicine · Mar 2024

    Case Reports

    Perihepatitis as an Initial Manifestation of Systemic Lupus Erythematosus.

    • Jun Nakamura, Takao Nagashima, Hiroaki Yazawa, Ayako Kokuzawa, and Kojiro Sato.
    • Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan.
    • Intern. Med. 2024 Mar 1; 63 (5): 739741739-741.

    AbstractA 25-year-old man presented with a fever and right upper quadrant abdominal pain. Computed tomography (CT) of the abdomen revealed diffuse perihepatic capsular enhancement, suggesting perihepatitis. Although the patient was a man, Fitz-Hugh-Curtis syndrome was suspected based on the CT findings. Treatment with several antibiotics was ineffective. Urinary tract infection was ruled out due to negative urinary bacterial screening and careful history taking. He was finally diagnosed with systemic lupus erythematous (malar rash, pleuritis, positive antinuclear antibody, and positive anti-ds-DNA antibody). Perihepatitis resolved quickly with high-dose prednisolone. Perihepatitis may be the first manifestation of SLE.

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