• Internal medicine · Mar 2024

    Case Reports

    Repeated Acute Exacerbations of Chronic Inflammatory Demyelinating Polyradiculoneuropathy Accompanied by Pain and Swelling in Distal Extremities.

    • Takenobu Murakami, Masafumi Kishi, Naoki Tokuda, Makoto Honda, and Ritsuko Hanajima.
    • Department of Neurology, Tottori Prefectural Kousei Hospital, Japan.
    • Intern. Med. 2024 Mar 1; 63 (5): 733737733-737.

    AbstractAn 81-year-old man experienced acute progression of weakness in the extremities accompanied by a fever, tenderness, and swelling in distal parts of the extremities. He had flaccid tetraparesis with fasciculations and general hyporeflexia. Nerve conduction studies indicated demyelinating sensorimotor neuropathy. A cerebrospinal fluid examination revealed elevated proteins without pleocytosis. Immunological treatments were effective, but his symptoms exhibited repeated relapse and remission phases. He was diagnosed with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with an acute onset. The highlight of this case is pain with inflammatory reaction recognized as red flags of CIDP, with the clinical course and electrophysiological findings compatible with CIDP.

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