• Internal medicine · Mar 2024

    Case Reports

    A Case of Multidrug-resistant IgA Vasculitis with Gastrointestinal Symptoms Successfully Treated with Intravenous Cyclophosphamide and Maintained with Mycophenolate Mofetil.

    • Haruka Miki, Hiroto Tsuboi, Fumina Kawashima, Toshiki Sugita, Taihei Nishiyama, Yuki Kuroda, Tomonori Sawabe, Nana Uematsu, Mayu Terasaki, Ayako Kitada, Fumika Honda, Ayako Ohyama, Mizuki Yagishita, Hiromitsu Asashima, Shinya Hagiwara, Yuya Kondo, and Isao Matsumoto.
    • Department of Rheumatology, Institute of Medicine, University of Tsukuba, Japan.
    • Intern. Med. 2024 Mar 1; 63 (5): 743747743-747.

    AbstractWe present the case of a 17-year-old woman with IgA vasculitis (IgAV) who presented with relapsing gastrointestinal (GI) symptoms that were refractory to glucocorticoid and combination therapy with cyclosporine A, azathioprine or mycophenolate mofetil (MMF). The patient responded well to remission induction with intravenous cyclophosphamide (IVCY) and was successfully maintained with MMF. Remission induction with IVCY followed by maintenance therapy with MMF was effective in a patient with multidrug-resistant IgAV with GI lesions.

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