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- Tomoyuki Hayashi, Takeshi Terashima, Masaki Nishitani, Noriaki Orita, Masaki Miyazawa, Akihiro Seki, Hidetoshi Nakagawa, Kouki Nio, Noriho Iida, Shinya Yamada, Hajime Takatori, Tetsuro Shimakami, and Taro Yamashita.
- Department of Gastroenterology, Kanazawa University Hospital, Japan.
- Intern. Med. 2024 Apr 1; 63 (7): 929935929-935.
AbstractA 29-year-old man with severe ulcerative colitis and gastroduodenitis was initially treated with oral mesalamine and high-dose intravenous steroid therapy; however, his epigastralgia and vomiting did not improve. After initiating infliximab, the patient experienced prompt improvement in symptoms and inflammation. Although steroids were effective for the colon, they proved ineffective for gastroduodenal lesions, highlighting the necessity for molecular-targeted agents, such as infliximab, in these cases. The timing for administering such agents should be carefully considered.
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